Macroamylasemia; a Dilemma in Morbidity

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Simultaneous macroamylasemia and macrolipasemia.

The first case of the simultaneous presence of macroamylasemia and macrolipasemia in a patient with gluten enteropathy (celiac disease) is described. Both macroenzymes were formed by association of polyclonal IgA with amylase and lipase. Both macroenzymes had molecular masses > 300 kDa.

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Macroamylasemia: A Simple Stepwise Approach

Typically, macroamylasemia is a condition of elevated serum amylase in the absence of symptomatic disease. However, in the presence of symptoms, especially of abdominal origin, it is important that this condition be identified accurately in order to avoid unnecessary treatment for pancreatitis or other related diseases. This report offers a review of the literature, a case example, and an algor...

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Macroamylasemia: rapid detection method.

A reliable method is presented for rapidly screening human sera to detect macroamylasemia. A mixture of the serum to be tested, Blue Dextran, and cytochrome c is filtered through a small column of cross-linked dextran gel (Sephadex G-100). Ainylase in the effluent fractions is detected by incubation with amylose and subsequent addition of iodine. Macroamylase, if present, is found in the blue-c...

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Macroamylasemia in a patient with acute appendicitis: a case report.

Macroamylasemia is a condition of persistent, elevated serum amylase activity with no apparent clinical symptoms of a pancreatic disorder. In Korea, however, no such case has been reported to date. We report a case of a 17-year-old female diagnosed with macroamylasemia and acute appendicitis. One day earlier, she developed epigastric and right lower quadrant abdominal pain. She was characterize...

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Macroamylasemia in a 4-year-old girl with abdominal pain

Macroamylasemia is a benign condition characterized by abnormally large-sized serum amylase; it has been reported to occur in 1–2% of the population. In macroamylasemia, a macromolecular complex consisting of amylase linked to immunoglobulins circulates in the plasma and usually causes hyperamylasemia with low or normal amylasuria. Macroamylasemia is extremely rare in children. We report a case...

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ژورنال

عنوان ژورنال: Balkan Medical Journal

سال: 2015

ISSN: 2146-3123,2146-3131

DOI: 10.5152/balkanmedj.2015.15320